书名：Neutrophils and altered matrix-induced generation of kallikrein singlet oxygen
出版时间：2015
出版社：Nova Science Publishers,
摘要
Neutrophils are the cells that protect our lives against fungi, bacteria, or thrombi. In fungal or bacterial sepsis the flowing blood is exposed to unphysiologic matrices that fold factor 12 and prekallikrein into F12a and kallikrein. These two enzymes start the contact system of coagulation (altered matrix (AM) - coagulation). The intrinsic ten-ase, factor 10a, thrombin, and micro-thrombi are formed. The neutrophils answer to increased blood concentrations of kallikrein (also a tissue enzyme) or micro-thrombi with intracellular NADPH-oxidase assembly and secretion of extracellular myeloperoxi
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目录
Preface vii
Chapter 1 Quantification of Micro-Thrombi Induced Blood ROS Generation 1
Chapter 2 Systemic Intravascular Coagulation 7
Chapter 3 Ultraviolet A Photons in the Late Phase of Oxidative Burst 23
Chapter 4 Kallikrein Modulates Singlet Oxygen Generation 29
Chapter 5 Metamizole Is a Strong Trigger of Intrinsic Coagulation 37
Chapter 6 Vitamin B1 (Thiamine) Triggers AM-Coagulation 43
Chapter 7 Vitamin B2 (Riboflavin) Triggers AM-Coagulation 49
Chapter 8 Vitamin B6 Triggers AM-Coagulation 57
Chapter 9 Vitamin B l2 Modulates AM-Coagulation 63
Chapter 10 Dramatic Increase of Blood ROS Generation by Vitamins B1, B2, B6, B12 73
Chapter 11 Drinking Water or Beverage Analysis for Intrinsic Coagulation Activation 89
Chapter 12 The True PAP Concentration in Plasma 93
Chapter 13 Stimulation of Blood Singlet Oxygen Generation by Serine Proteases 99
Chapter 14 Applied Biochemistry of the BRGA 115
Chapter 15 Neutrophils in Fibrinolysis 127
Chapter 16 Hemostasis Activation in Inflammation: Kallikrein, Thrombin,1ΔO2* 151
Index 159
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馆藏单位
中国医科院医学信息研究所
